Other Advanced Testing

EndoPAT® TEST—SCREENING FOR CARDIOVASCULAR DISEASE

There are real beginnings to cardiovascular and other systemic diseases, but symptoms are often silent in early stages, as well as in some advanced stages. A proactive approach to one’s health can uncover the current state of endothelial health so that, if necessary, the individual can seek appropriate treatment and/or course of action. What is endothelial health and why is it important? How do you know if you have endothelial dysfunction?

Endothelial Dysfunction—Indicator of Your Risk Factor

Endothelial dysfunction is the medical term for arterial function, or the ability of the endothelial cells located in the inner lining of blood vessels to dilate sufficiently to regulate normal blood flow. The endothelium protects against the buildup of plaque that leads to hardening and narrowing of the arteries, known as atherosclerosis.

Endothelium dysfunction can be evaluated to determine if cardiovascular disease is in the developing stages. If discovered in its earliest stages, this condition is called subclinical atherosclerosis and can be reversed with proper treatment. If left untreated, this condition becomes atherosclerosis, which restricts blood flow and results in cardiovascular disease, manifesting as heart attack, stroke/TIA, and/or peripheral vascular disease.

In addition to cardiovascular morbidity and mortality, the endothelium has great impact on other systemic disease processes. Endothelial dysfunction can initiate an inflammatory process that leads to other systemic diseases, including metabolic syndrome, renal failure, sleep apnea, claudication, gangrene, preeclampsia toxemia, and erectile dysfunction.

PAT Signal and EndoPAT®

A procedure that noninvasively measures peripheral artery tone (PAT) was developed to capture what is referred to as the “PAT signal.” The leading medical device used to measure this signal is called the EndoPAT®. After successful demonstration that PAT technology is equivalent to an invasive catheterization performed to evaluate endothelial function in the coronary arteries, the EndoPAT® was cleared by the FDA.

The EndoPAT® quickly and painlessly measures the PAT by recording arterial pulsatile changes in the fingertip during a simple 15-minute test performed here in our facility. The test is as easy as taking a blood pressure reading and involves no radiation or nuclear exposure. The resulting number is called the EndoScore, with a low score of 1.67 or below indicating the need for further examination by a cardiologist.

A joint study conducted by the Mayo Clinic and Tufts University show that the EndoPAT® test is a highly accurate quantifier and highly predictive of a major cardiac event such as a heart attack or stroke for low-to-moderate risk individuals. Prior to development of EndoPAT®, there was no simple test for endothelial dysfunction. This test now provides the opportunity to address a potential serious condition, i.e., cardiovascular disease, early enough to hopefully avoid its consequences of heart attack, stroke, or peripheral artery disease.

Schedule your EndoPAT® test to see if you are at risk and, if so, work with your physician to embark on a prevention program. Contact RevitaLife at 941-377-4555 or use our online contact form to get started.

LIPOPROTEIN PARTICLE PROFILE (LPP)—CHOLESTEROL LEVEL TESTING

High cholesterol is a silent health risk that can be deadly because abnormal cholesterol levels are a major risk factor for heart disease and stroke. A variety of factors can affect a person’s cholesterol levels:

  • Diet—Saturated fat and cholesterol in the food you eat increase cholesterol levels.
  • Weight—Being overweight is a risk factor for heart disease and can also increase cholesterol. Losing weight can help lower total cholesterol and LDL (the “bad” cholesterol) levels while increasing HDL (the “good” cholesterol).
  • Exercise—Regular exercise can lower LDL cholesterol and raise HDL cholesterol.
  • Age and gender—Cholesterol levels rise with age. Before menopause, women tend to have lower total cholesterol levels than men of the same age. After menopause, however, women’s LDL levels tend to rise.
  • Diabetes—Poorly controlled diabetes increases cholesterol levels.
  • Heredity—The genes partly determine how much cholesterol the body makes. High blood cholesterol can run in families.
  • Other causes—Certain medications and medical conditions can cause high cholesterol.

A variety of vitamins and natural cholesterol healing products—minerals, antioxidants, herbs, and other nutrients—are considered to be natural sources to reduce cholesterol, while also contributing to improved cholesterol health. Published studies involving over 30,000 participants show that policosanol, a plant-derived nutrient, may actually block cholesterol formation in the liver, heart, and fatty tissue. In addition, it may effectively reduce LDL cholesterol, raise HDL cholesterol, and balance total cholesterol. Omega-3 fish oil and Kyolic garlic (aged to enhance nutritional value, remove pungent odor, and make it gentler on the stomach) effectively inhibit LDL cholesterol while also boosting heart health.

While an individual’s total cholesterol number may be an indicator of risk for cardiovascular disease (CVD), it is important to assess the number and density of LDL particles. Even when a person’s total cholesterol may be considered “normal,” LDL may be higher in proportion to HDL, thus increasing the risk of CVD because there is greater probability of penetration of cholesterol in the artery wall. LDL is the carrier of cholesterol throughout the body, resulting in plaque formation and development of CVD.

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LPP Plaque Formation, Courtesy of SpectraCell

The LPP, developed by SpectraCell Laboratories, Inc., is one of the most advanced and sophisticated lab tests available for testing cholesterol levels. However, measuring cholesterol alone does not provide the complete picture and can be misleading. The LPP accurately measures the size, density, and number of lipoprotein particles and identifies hidden cardiovascular risk due to the formation of rupture-prone plaque. A simple blood test can assist the physician in predicting which patients are at greater risk for heart attack or stroke.

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Courtesy of SpectraCell

The National Cholesterol Education Program (NCEP) suggests that a simple blood test to measure and evaluate the LDL subgroups is crucial for a thorough and accurate assessment of cardiovascular risk. The following risk factors have been identified by the NCEP:

  • Small, dense LDL—atherogenic particles that are easily oxidized and penetrate the arterial endothelium to form plaque
  • Lp(a)—small, dense LDL that is involved in thrombosis
  • RLP (remnant lipoprotein—very atherogenic with a similar composition and density to plaque and believed to be the building block of plaque; does not need to be oxidized like other LDL particle
  • HDL2b—positively correlates with heart health because it is an indicator of how well excess lipids are removed

At RevitaLife, we can initiate the blood test for submission to SpectraCell Laboratories, which performs the analysis and produces the Lipoprotein Particle Profile, thus giving you and your physician a more comprehensive assessment of your cardiovascular risk.

To get more information about the LPP test, call RevitaLife at 941-377-4555 or click here to use our convenient online Contact Us form.

LIVER TESTING

The liver is one of the most important organs in the body because it processes everything we consume and filters harmful substances from the blood. Some fat in the liver is normal, but when fat content is more than 5 to 10 percent of liver weight, it is classified as fatty liver. Fatty liver affects 10 to 20 percent of our population, and that number is increasing due to the rapidly rising rate of obesity and diabetes. The most common cause of fatty liver is heavy drinking and alcoholism. When alcohol is not a contributing factor, physicians look to other reasons for fatty liver.

How to Improve Liver Health

  • Avoid or limit alcoholic beverages.
  • Maintain a healthy weight.
  • Control your blood sugar.
  • Manage your cholesterol.
  • Eat a healthy diet consisting of fewer fatty foods, less sugar, less red meat, and more whole grains, fruits, and vegetables.

Stages of Liver Damage

Fatty liver usually has no apparent symptoms, but excessive fat in the liver can interfere with liver function and lead to liver inflammation, causing poor appetite, abdominal discomfort or pain, weakness, fatigue, and confusion. Ongoing, repeated damage to the liver leads to accumulation of scar tissue (liver fibrosis) and then to cirrhosis (permanent scarring).

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Diagnosing Liver Disease: New Technology Tracks Liver Hardness and Fat Content

Several tests may be performed to detect issues with the liver: physical examination by a physician, blood tests to check for elevated liver enzymes, imaging studies (ultrasound, CT scan, and MRI), and liver biopsy. While some of these tests may confirm a fatty liver, they do not monitor progression of liver inflammation or damage to the liver.

When a liver is compromised, it is important to track both the hardness of the liver and the level of fat present in the liver. FibroScan® is the tradename for an ultrasound examination that specifically assesses liver hardness and stiffness (fibrosis) and level of fat (steatosis). This noninvasive exam uses technology called Vibration-Controlled Transient Elastrophy (VCTE) to measure liver fibrosis and Controlled Attenuation Parameter (CAP) to assess and quantify steatosis.

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With VCTE, an ultrasound probe emits a mechanical pulse at the surface of the skin to measure the condition of the liver through sound waves. The computer displays a two-dimensional picture of the liver and analyzes the data from at least ten separate readings taken of the liver. An immediate measurement of the hardness of the liver, using a range from 1.5 to 75 kPa correlated to fibrosis, is given to the physician. The harder the liver, the more serious the fibrosis is likely to be. Cirrhosis becomes a concern at 12 kPa.

CAP is currently the only noninvasive means to assess and quantify fat in the liver (steatosis). Prior to the development of CAP, conventional ultrasound was the only way to detect the presence of steatosis, and quantification was not even possible. CAP is calculated only if the liver hardness measurement is valid. The final CAP result is the median of at least ten valid CAP measurements. CAP and VCTE are performed simultaneously in the same liver volume and do not extend the duration of the test.

FibroScan® is easy, painless, and quick, taking less than ten minutes. It and assists in diagnosing and monitoring the progression of liver disease. When close follow-up is needed, the exam may be safely repeated every 6-12 months. This follow-up helps monitor the progression of liver disease and, if treatment or lifestyle changes has taken place, helps to determine how successful those measures have been.

To get more information about FibroScan® or to schedule your liver evaluation, call RevitaLife at 941-377-4555 or click here to use our convenient contact form.

TELOMERE TESTING FOR AGE MANAGEMENTlaser treatment

A telomere is an area of genetic material at the end of a chromosome, which protects the end of the chromosome from deterioration when a cell replicates. Telomeres become shorter as a cell ages and, eventually, they become so short that the cell stops dividing and ultimately dies; this is a normal biological process. Three U.S. scientists, Elizabeth Blackburn, Carol W. Greider, and Jack W. Szostack, discovered the key aspects of this process and won the Nobel prize in medicine in 2009.

Telomere testing, a new foundation for age management, can determine the length of a person’s telomeres to assess the person’s biological age. The Patient Telomere Score is the calculation obtained by the test—the higher the telomere score, the “younger” the cell. Serial evaluation of telomere length is an indicator of how rapidly one ages relative to a defined “normal” population.

Shorter telomeres have been associated with metabolic abnormalities, obesity, and degenerative diseases including cancer, dementia, and cardiovascular disease. Therapies and lifestyle modifications directed at slowing the loss of telomere length may slow aging and age-related diseases:

  • Diet—A diet that increases oxidative stress, referred to as an inflammatory diet, shortens telomeres faster. The inflammatory diet is high in refined carbohydrates, fast foods, processed foods, sodas, artificial sweeteners, trans fats and saturated fats. A diet rich in antioxidants reduces oxidative stress and thus slows telomere shortening; such a diet includes fresh, raw fruits and vegetables; monounsaturated fats; omega-3 fatty acids; and high quality vegetable proteins. It is also important to maintain proper levels of micronutrients, especially Vitamin D.
  • Body weight—Ideal body weight and low body fat of less than 22% for women and 16% for men should be maintained.
  • Other factors—Also important are decreasing visceral fat, regular aerobic and resistance exercise (at least one hour per day), at least eight hours of sleep per night, stress reduction, and cessation of all forms of tobacco.

Telomere testing should be done annually to evaluate the rate of aging and make appropriate adjustments in therapies. For more information, call RevitaLife today at 941-377-4555 to schedule a consultation or click here to use our handy contact form.

BIOENERGY TESTING FOR AGE MANAGEMENT

Aging is not the same as getting older; it is the progressive deterioration of physical and mental functions. While we can’t stop aging, we can control the rate and extent to which aging occurs.

The ability of the body to create energy controls aging. Energy is produced in the mitochondria of each cell. These tiny bubble-shaped structures convert oxygen to energy by burning fat or sugar. The root cause of disease is poor mitochondrial function. Decreased energy production comes from decreased mitochondrial efficiency and decreased fat metabolism. To slow or even reverse aging and disease, you must address the problem of mitochondrial energy production.

Bioenergy testing is a breakthrough anti-aging tool. It can measure your mitochondrial function to determine if your body is efficiently producing energy. The test is performed while on an exercise bike for 10-15 minutes. From a resting state, you progress to more difficult exercise as our state-of-the-art equipment takes measurements of how much oxygen you are using and how much carbon dioxide you are producing.

This information is important because:

  • Mitochondrial efficiency is determined by oxygen consumption.
  • Fat metabolism is determined by carbon dioxide production.
  • The ratio of oxygen consumption to carbon dioxide production indicates optimum carbohydrate intake.
  • Overall strength is a function of the amount of work you can produce per amount of energy you make.

The bioenergy algorithm can calculate the test results regarding your:

  • Resting mitochondrial efficiency
  • Resting fat metabolism
  • Maximum mitochondrial efficiency
  • Maximum fat metabolism

The results have immediate clinical relevance and are key indicators of your:

  • Heart and lung function
  • Overall strength and biological age
  • Optimum exercise levels
  • Carbohydrate and total calorie intake

Attaining Optimum Energy

If your mitochondria are functioning at optimal levels, you have great news. If the bioenergy test results indicate that your mitochondrial function is less than optimal, the medical and nutritional team at RevitaLife can tailor a total lifestyle program to restore energy production to more optimal levels. This program will be individualized to address your specific hormonal, nutritional, dietary, and exercise needs.

If you are ready to get the most out of your life and want to live without commitment to large amounts of medication, you need to monitor your health and slow or stop degenerative aging and disease. The bioenergy test can be your first step to starting a health program that focuses on your overall health and not just managing your symptoms.

Make an appointment for bioenergy testing at RevitaLife. Get tested and start implementing your custom anti-aging protocol today. Within just a few months, you will be feeling better and have higher energy levels than you have had in years. Call RevitaLife at 941-377-4555 or click here to contact us regarding your bioenergy test.


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